Prostate biopsies endothelin-1 expression: pt3a stage prognostic factor?
T Perez, J Menard, K Joseph, P Birembaut… - Progres en Urologie …, 2010 - europepmc.org
T Perez, J Menard, K Joseph, P Birembaut, F Staerman
Progres en Urologie: Journal de L'association Francaise D'urologie et …, 2010•europepmc.org… In multivariate analysis, biopsy ET-1 PCa expression was an independent risk factor of
pT3a stage with specificity 79 %, sensibility 69 %, predictive positive value 77 % and
negative positive value 72 %. Combined with initial PSA > or =7, values were respectively
100 %, 76.9 %, 100 % and 57.1 %. … Endothelin-1 (ET-1) prostate cancer biopsy
expression in our study was an independent prognostic factor of extracapsular stage (pT3a).
Further studies will assess the relevance of ET-1 expression study in clinically localised …
pT3a stage with specificity 79 %, sensibility 69 %, predictive positive value 77 % and
negative positive value 72 %. Combined with initial PSA > or =7, values were respectively
100 %, 76.9 %, 100 % and 57.1 %. … Endothelin-1 (ET-1) prostate cancer biopsy
expression in our study was an independent prognostic factor of extracapsular stage (pT3a).
Further studies will assess the relevance of ET-1 expression study in clinically localised …
Aim
The study evaluated the immunohistochemistry expression of endothelin-1 (ET-1) by prostate cancer (PCa) in prostate biopsies as an extracapsular stage (pT3a) prognostic factor.
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